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Mounjaro Stomach Pain: Why It Happens + How to Treat It

Mounjaro is one of several weight loss drugs out there designed to help treat type 2 diabetes to improve glycemic control. The scientific name of this powerhouse drug is Terzepatide, the same drug behind another popular brand name diabetes medication: Zepbound. 

And while Mounjaro was decided to do a lot of good, like any medication, it comes with its pros and cons. Yes, Mounjaro has been linked to some serious side effects that each patient should discuss with their doctor when weighing whether this medication is right for them. But we’re here to talk about a side effect that isn’t necessarily serious, but it is uncomfortable and can interfere with day to day life.

We’re talking about Mounjaro stomach pain.

But what causes stomach pain in users of this popular GLP-1 weight loss drug? How does the medicine work anyway? How bad is the stomach pain, and what can you do to stop it?

Today we’ll be discussing all of this and more, including strategies to help soothe stomach pain, like:

  • What you can include in your diet to support stomach health
  • When to take Mounjaro for the greatest impact and lowest chance of side effects
  • Supplements that can support digestive health for a happy gut

Stomach pain is no fun – so why does a medication that is designed to help people regulate their metabolism of certain compounds cause so much of it for some people? Let’s dive in. 

What's the Deal with Mounjaro?

Let's kick things off by getting to know Mounjaro a little better. This powerhouse drug is a GLP-1 receptor agonist, meaning it works its magic by mimicking the action of a natural hormone in your body called glucagon-like peptide-1 (GLP-1). GLP-1 plays a crucial role in regulating blood sugar levels and appetite, making it a key player in the weight loss game.

By activating GLP-1 receptors in your brain, Mounjaro helps you feel fuller for longer, curbing those pesky cravings and ultimately leading to fewer calories consumed. It also slows down the emptying of your stomach and helps regulate insulin production, resulting in better blood sugar control and, you guessed it, weight loss.

Unpacking Mounjaro Stomach Pain: What's Going On Inside?

Now, let's address the elephant in the room – why does Mounjaro sometimes cause stomach pain? Well, my friends, the answer lies in a few key factors. One of the main culprits is the drug's effect on gastric motility, or the movement of food through your digestive tract.

Mounjaro has a knack for slowing down the emptying of your stomach, which can leave you feeling uncomfortably full, bloated, and downright queasy, especially after chowing down on a meal. Additionally, some users may experience bouts of nausea or even vomiting as a result of Mounjaro's impact on gastrointestinal function.

Another piece of the puzzle is the drug's interaction with GLP-1 receptors in your gut. While activating these receptors can have positive effects on weight loss and blood sugar control, it can also throw a wrench into the gears of your digestive system, leading to symptoms like abdominal pain, cramping, and diarrhea.

Something as simple as keeping hydrated and eating an appropriate amount of calories based on the meal plan you create with your healthcare provider can help cut down on stomach pain caused by weight loss drugs like Moujaro.

Strategies for Soothing Mounjaro Stomach Pain: Finding The Right Solution for You

We’ve identified some of the root causes of Mounjaro stomach pain, but what is there to be done about it? Some over the counter medications can reduce digestive symptoms like bloating and stomach pain – you’ve probably got some Tums or Gas-X in your cabinet right now. But there are ways to protect your stomach before the pain starts, too. Here are some tried-and-true strategies to help you find relief and get back to feeling your best.

Start Low, Go Slow

If you're experiencing severe stomach pain or other unpleasant side effects from Mounjaro, don't be afraid to have a chat with your healthcare provider about adjusting your dosage.Many of the side effects of Mounjaro are at their worst when you first start taking it, and they can flare up when when your dose increases. But starting with a lower dose and ramping up the dosage bit by bit can help your body adjust to having the medication in its system. 

Translation? A smoother transition, less discomfort, and fewer side effects.

Switch It Up

Doing the same old thing every time gets boring, doesn’t it? But when it comes to choosing a place for your Mounjaro injection, switching up the injection site is actually a key factor for reducing side effects

Granted when it comes to switching injection sites, we’re talking more about reducing injection site irritation than addressing the stomach pain that sometimes comes along with a Mounjaro prescription, but hey. We want to reduce discomfort from the feet up, so this is still an important step.

Keep the harsher ingredients that might be upsetting your tummy from hitting your stomach lining directly when you time your Mounjaro injection for after you’ve eaten a good, healthy meal. 

Timing Is Everything 

Many medications don’t feel so great on an empty stomach, and Mounjaro is no different. With capsule medications, taking the medication with food gives it a little cushion, preventing the drug’s harsher ingredients from hitting an empty stomach and causing unpleasant side effects like nausea and vomiting.

Even though it’s an injection, taking Mounjaro with food can be a game-changer when it comes to soothing stomach woes. Downing your dose alongside a meal provides a protective barrier between the drug and your stomach lining, helping to reduce irritation and discomfort.

Stay Hydrated

This might not seem like a solution for stomach trouble – who wants water sloshing around in there when your stomach is upset? But particularly when your stomach pain comes with other unpleasant symptoms – like vomiting or diarrhea – staying hydrated is an essential part of soothing your stomach. 

Dehydration can exacerbate stomach pain and digestive issues, so be sure to drink plenty of water throughout the day. Aim for at least eight glasses a day and steer clear of caffeine and alcohol, which can further deplete your body's hydration levels.

Fiber Is Your Friend

Stomach pain isn’t a one size fits all side effect. When it comes to GLP-1s like Mounjaro, not every patient will have the same type of stomach pain. Some people might deal with heart burn and reflux, others might find themselves with vomiting or diarrhea. And still others will find themselves dealing with constipation as a side effect of their Mounjaro prescription.

Incorporating more fiber-rich foods into your diet can work wonders for taming Mounjaro-induced stomach pain. Think whole grains, fruits, veggies, and legumes – these fiber-packed powerhouses can help regulate digestion and keep things moving smoothly.

Another option? Up your fiber intake with gut-support capsules or drink mix, like Dr. Emil’s Total Gut Complex capsules or Dr. Emil’s Multi Collagen Peptides + Gut Health drink powder. 

Consider Probiotics 

Bloating and stomach pain can be caused by many things, including an upset in your gut’s flora. Food that’s rich in probiotics and prebiotics can be a delicious way to stop stomach pain in its tracks. Foods like kefir, miso, kombucha, yogurt, and pickles are naturally full of helpful prebiotics and probiotics that help regulate your digestive system. 

Not getting enough probiotics in your diet? Or maybe you’re also dealing with a decreased appetite? Probiotic supplements containing beneficial bacteria can help restore balance to your gut microbiome and alleviate symptoms of gastrointestinal discomfort as well. Look for a high-quality probiotic with multiple strains of bacteria and make it a part of your daily routine.

Dr. Emil’s Total Gut Complex contains prebiotics, probiotics, and postbiotics to keep your stomach feeling its best. Prebiotics stimulate the good bacteria, probiotics support overall digestive health, and postbiotics strengthen the gut barrier. Together, it’s a recipe for improved stomach comfort.

Your body will tell you what it needs if you listen – so see what improves your stomach pain and what makes it worse. It is your number one ally in building a plan that works for you – and doesn’t cause you lots of stomach discomfort. 

Listen to Your Body

Above all else, pay attention to what your body is telling you. If certain foods or activities seem to exacerbate your stomach pain, take note and make adjustments accordingly. Trust your gut (pun intended) and don't hesitate to seek guidance from a healthcare professional if needed.

Mounjaro stomach pain isn’t fun, but there are simple swaps you can make to soothe your stomach from the start. 

Experiencing stomach pain or discomfort while taking Mounjaro can be a real bummer, but armed with the right knowledge and strategies, you can overcome these challenges and continue on your weight loss journey with confidence. By understanding the mechanisms behind Mounjaro stomach pain and taking proactive steps to address it, you can minimize side effects and maximize the benefits of this powerful drug.

Remember, you're not alone in this journey. Reach out to your healthcare provider for guidance and support, and don't hesitate to lean on your fellow wellness warriors for encouragement along the way. Together, we've got this!

Stay strong, stay resilient, and keep pushing forward towards your health and wellness goals. You've got what it takes to conquer Mounjaro stomach pain and emerge stronger on the other side.

You should consult a licensed health care professional before starting any supplement, dietary, or exercise program, especially if you are pregnant or have any pre-existing injuries or medical conditions.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases.

Author: Dr. Emil Hodzovic

Holding degrees in both medicine and Sports + Exercise Science from renowned research institution Cardiff University, Dr. Emil Hodzovic has the dual distinction of being a practicing clinician and respected authority in nutrition and supplementation.

During his parallel careers as a personal trainer and professional athlete, Dr. Emil recognized a critical flaw in the supplement space: too much emphasis on appearance and performance—and zero concern for making holistic health and happiness accessible to everyone.

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